75000 - Document - Document and Entity Information
link:presentationLink
link:calculationLink
link:definitionLink
75010 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75020 - Statement - CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) (Parenthetical)
link:presentationLink
link:calculationLink
link:definitionLink
75030 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75040 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75050 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited)
link:presentationLink
link:calculationLink
link:definitionLink
75060 - Statement - CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) 2
link:presentationLink
link:calculationLink
link:definitionLink
995455 - Disclosure - Organization
link:presentationLink
link:calculationLink
link:definitionLink
995465 - Disclosure - Summary of Significant Accounting Policies
link:presentationLink
link:calculationLink
link:definitionLink
995475 - Disclosure - Fair Value Measurements
link:presentationLink
link:calculationLink
link:definitionLink
995485 - Disclosure - Available-for-sale Securities
link:presentationLink
link:calculationLink
link:definitionLink
995495 - Disclosure - Balance Sheet Components
link:presentationLink
link:calculationLink
link:definitionLink
995505 - Disclosure - Intangible Assets and Goodwill
link:presentationLink
link:calculationLink
link:definitionLink
995515 - Disclosure - Commitments and Contingencies
link:presentationLink
link:calculationLink
link:definitionLink
995525 - Disclosure - Liability Related to the Sale of Future Royalties
link:presentationLink
link:calculationLink
link:definitionLink
995535 - Disclosure - Term Loan Facility
link:presentationLink
link:calculationLink
link:definitionLink
995545 - Disclosure - Common Stock
link:presentationLink
link:calculationLink
link:definitionLink
995555 - Disclosure - Stock-based Compensation
link:presentationLink
link:calculationLink
link:definitionLink
995565 - Disclosure - Net Loss Per Share Attributable to Common Stockholders
link:presentationLink
link:calculationLink
link:definitionLink
995575 - Disclosure - Subsequent events
link:presentationLink
link:calculationLink
link:definitionLink
995585 - Disclosure - Summary of Significant Accounting Policies (Policies)
link:presentationLink
link:calculationLink
link:definitionLink
995595 - Disclosure - Summary of Significant Accounting Policies (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995605 - Disclosure - Fair Value Measurements (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995615 - Disclosure - Available-for-sale Securities (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995625 - Disclosure - Balance Sheet Components (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995635 - Disclosure - Intangible Assets and Goodwill (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995645 - Disclosure - Commitments and Contingencies (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995655 - Disclosure - Liability Related to the Sale of Future Royalties (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995665 - Disclosure - Common Stock (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995675 - Disclosure - Stock-based Compensation (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995685 - Disclosure - Net Loss Per Share Attributable to Common Stockholders (Tables)
link:presentationLink
link:calculationLink
link:definitionLink
995695 - Disclosure - Organization - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995705 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995715 - Disclosure - Summary of Significant Accounting Policies - Schedule of Significant Segment Expenses (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995725 - Disclosure - Fair Value Measurements - Schedule of Financial Assets Measured at Fair Value (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995735 - Disclosure - Fair Value Measurements - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995745 - Disclosure - Available-for-sale Securities - Summary of Amortized Cost and Estimated Fair Value of Available-for-sale Securities and Cash Equivalents and Gross Unrealized Gains and Losses (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995755 - Disclosure - Available-for-sale Securities - Summary of Amortized Cost and Estimated Fair Value of Available-for-sale Securities by Contractual Maturity (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995765 - Disclosure - Balance Sheet Components - Schedule of Property and Equipment, Net (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995775 - Disclosure - Balance Sheet Components - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995785 - Disclosure - Balance Sheet Components - Schedule of Accrued Expenses and Other Current Liabilities (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995795 - Disclosure - Intangible Assets and Goodwill - Schedule of Intangibles Assets, Net (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995805 - Disclosure - Intangible Assets and Goodwill - Schedule of Intangibles Assets, Net (Details) 2
link:presentationLink
link:calculationLink
link:definitionLink
995815 - Disclosure - Intangible Assets and Goodwill - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995825 - Disclosure - Intangible Assets and Goodwill - Schedule of Future Amortization Expense (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995835 - Disclosure - Intangible Assets and Goodwill - Schedule of Goodwill (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995845 - Disclosure - Commitments and Contingencies - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995855 - Disclosure - Commitments and Contingencies - Summary of Balance Sheet Classification of Operating Lease Liabilities (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995865 - Disclosure - Commitments and Contingencies - Summary of Balance Sheet Classification of Operating Lease Liabilities (Details) 2
link:presentationLink
link:calculationLink
link:definitionLink
995875 - Disclosure - Commitments and Contingencies - Summary of Components of Lease Costs (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995885 - Disclosure - Commitments and Contingencies - Schedule of Maturities of Operating Lease Liabilities (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995895 - Disclosure - Commitments and Contingencies - Schedule of Maturities of Operating Lease Liabilities (Details) 2
link:presentationLink
link:calculationLink
link:definitionLink
995905 - Disclosure - Liability Related to the Sale of Future Royalties - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995915 - Disclosure - Liability Related to the Sale of Future Royalties - Schedule of Activity of Liability Related to the Sale of Future Royalties (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995925 - Disclosure - Term Loan Facility - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995935 - Disclosure - Common Stock - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995945 - Disclosure - Common Stock - Schedule of Common Stock for Future Issuance (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995955 - Disclosure - Stock-based Compensation - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995965 - Disclosure - Stock-based Compensation - Summary of Option Activity Under the Plan (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995975 - Disclosure - Stock-based Compensation - Summary of RSUs Activity Under the Plan (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995985 - Disclosure - Stock-based Compensation - Summary of Total Stock-Based Compensation Expense Related to Stock Options, RSUs and Employee Stock Purchase Plan (Details)
link:presentationLink
link:calculationLink
link:definitionLink
995995 - Disclosure - Net Loss Per Share Attributable to Common Stockholders - Computation of Basic and Diluted Net Loss Per Share Attributable to Common Stockholders (Details)
link:presentationLink
link:calculationLink
link:definitionLink
996005 - Disclosure - Net Loss Per Share Attributable to Common Stockholders - Schedule of Outstanding Potentially Dilutive Shares Excluded from Calculation of Diluted Net Loss Per Share (Details)
link:presentationLink
link:calculationLink
link:definitionLink
996015 - Disclosure - Subsequent events - Additional Information (Details)
link:presentationLink
link:calculationLink
link:definitionLink
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Restricted stock units vested
Other Research and Development Expense
Other research and development costs
Accrued Employee Benefits, Current
Accrued compensation
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Statement of Financial Position Location, Balance [Domain]
Balance Sheet Location
Increase (Decrease) in Accounts Payable
Accounts payable
Increase (Decrease) in Accounts Payable, Total
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities
Plan Name [Axis]
Plan Name
Entity Current Reporting Status
Entity Current Reporting Status
Class of Financing Receivable [Axis]
Exercise of warrants
Proceeds from Warrant Exercises
U.S. Government and Agency Securities
US Government Agencies Debt Securities [Member]
Operating expenses:
Operating Expenses [Abstract]
Tier Three [Member]
Tier three.
Tier Three
Fair Value, Inputs, Level 2 [Member]
Level 2
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Common Stock, Shares Authorized
Common stock, shares authorized
Liability Class
Fair Value by Liability Class [Domain]
Document Fiscal Period Focus
Document Fiscal Period Focus
Two Thousand Twenty Four Atm Program [Member]
Two thousand twenty four Atm program.
2024 ATM Program
Entity Shell Company
Entity Shell Company
Segment Reporting, Policy [Policy Text Block]
Segment Reporting
Cash and Cash Equivalent
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Common Stock, Shares, Issued
Common stock, shares, issued
Common Stock, Shares, Issued, Total
Shares of common stock issued
Asset Class [Domain]
Asset Class
Statement [Table]
Statement [Table]
Restricted Cash, Noncurrent
Restricted cash
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of-use assets obtained in exchange for operating lease liabilities
Proceeds from Debt, Net of Issuance Costs
Proceeds from term loan debt, net of issuance costs
Statement [Line Items]
Statement [Line Items]
Warrant [Member]
Warrants
Entity Filer Category
Entity Filer Category
Total liabilities and stockholders' equity
Liabilities and Equity
Tranche Four
Tranche Four [Member]
Tranche four.
Payments to Acquire Marketable Securities
Purchases of marketable securities
Payments to Acquire Marketable Securities, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Weighted-average exercise price, Options vested and exercisable
Long-Lived Tangible Asset [Axis]
Long-Lived Tangible Asset
Warrant liabilities
Warrant liability.
Warrant Liability [Member]
Concentration of credit risk and other risks and uncertainties.
Concentration Of Credit Risk And Other Risks And Uncertainties Policy [Text Block]
Concentration of Credit Risk and Other Risks and Uncertainties
Subsequent Event [Line Items]
Restricted cash.
Restricted Cash [Member]
Restricted Cash
Goodwill
Goodwill
Goodwill, Total
Balance at December 31, 2024
Balance at September 30, 2025
Royalty Purchase Agreement [Member]
Royalty purchase agreement.
Royalty Purchase Agreement
Increase Decrease In Operating Lease Liabilities
Increase (decrease) in operating lease liabilities.
Increase in operating lease liabilities
Investment Income, Interest
Interest income
Geographical [Domain]
Geographical
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Property, Plant and Equipment [Line Items]
Property Plant And Equipment [Line Items]
Finite-Lived Intangible Asset, Useful Life
Developed technology - tri-complex platform, Weighted-average remaining useful life
Five Hundred Saginaw Drive Redwood City California [Member]
500 Saginaw Drive, Redwood City, California.
The 500 Building
Maturity date, description
Debt Instrument, Maturity Date, Description
Number of Shares underlying options, Options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Number of Shares underlying options, Options granted
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Computation of Basic and Diluted Net Loss Per Share Attributable to Common Stockholders
Net loss per share attributable to common stockholders, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Number of Shares underlying options, Ending balance
Number of Shares underlying options, Beginning balance
Liabilities, Current
Total current liabilities
Accounts receivable
Increase (Decrease) in Accounts Receivable
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Salary and Wage, Excluding Cost of Good and Service Sold
Salary and Wage, Excluding Cost of Good and Service Sold, Total
Salaries and other employee-related expenses
Servicing Asset at Amortized Cost
Servicing Asset at Amortized Cost, Ending Balance
Servicing Asset at Amortized Cost, Beginning Balance
Amortized cost
Adjustments To Additional Paid In Capital Number Of Warrants Issued
Adjustments to additional paid in capital number of warrants issued.
Issuance of common stock pursuant to exercise of prefunded warrants, shares
Accrued expenses and other current liabilities.
Accrued Expenses And Other Current Liabilities [Abstract]
Proceeds From Issuance Of Common Stock Gross
Proceeds from issuance of common stock gross.
Proceeds from issuance of common stock gross
Issuance costs
Payments of Debt Issuance Costs
Debt issuance costs
Accounting Standards Update [Axis]
Accounting Standards Update
Consolidation Items [Domain]
Equity, Attributable to Parent [Abstract]
Stockholders' equity:
Entity Small Business
Entity Small Business
Stock issued during period shares vesting of restricted stock.
Stock Issued During Period Shares Vesting Of Restricted Stock
Issuance of common stock related to vesting of restricted stock units, shares
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Accounting Standards Update 2016-02 [Member]
ASC 842
Goodwill, Foreign Currency Translation and Measurement Period Adjustments
Adjustment
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Number of Shares underlying options, Options cancelled and forfeited
Tranche Five [Member]
Tranche five.
Tranche Five
Share-Based Payment Arrangement [Text Block]
Stock-based Compensation
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Non Cash Interest Expense Associated With the Sale of Future Royalties
Non-cash interest expense associated with the sale of future royalties.
Non-cash interest expense associated with the sale of future royalties
Lessee, Lease, Description [Line Items]
Lessee Lease Description [Line Items]
Amendment Flag
Amendment Flag
Accrued research and development expense current.
Accrued Research And Development Expense Current
Accrued research and development
Corresponding Tranche
Corresponding Tranche [Member]
Corresponding tranche.
Payments of deferred offering costs.
Payments Of Deferred Offering Costs
Deferred offering costs
Liabilities and stockholders' equity
Liabilities and Equity [Abstract]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Tranche Three [Member]
Tranche three.
Tranche Three
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation
Net cash used in operating activities
Increase (Decrease) in Operating Lease Liability
Operating lease liability
Increase in operating lease liability
Debt Instrument, Redemption Price, Percentage
Debt instrument redemption price percentage
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Schedule of Common Stock for Future Issuance
Schedule of common stock reserved for future issuance table text block.
Schedule Of Common Stock Reserved For Future Issuance Table [Text Block]
Common Stock [Member]
Common Stock
Earn out shares
Earn Out Shares [Member]
Earn out shares [Member]
Earn-out shares
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Weighted-average exercise price, Options granted
Lessee, Operating Lease, Liability, to be Paid, Year Three
2028
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Less: accumulated depreciation and amortization
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Debt Securities, Available-for-Sale [Line Items]
Schedule Of Available For Sale Securities [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Fair Value Hierarchy and NAV [Axis]
Fair Value Hierarchy and NAV
Earnings Per Share [Abstract]
Name of Property [Axis]
Name of Property
Goodwill and Intangible Assets Disclosure [Text Block]
Intangible Assets and Goodwill
At The Market Equity Offering [Member]
At the market equity offering.
At-the-market Offering
Statement of Financial Position Location, Balance [Axis]
Balance Sheet Location
Fair value level1 level2 level 3 transfers amount.
Fair Value Level1 Level2 Level3 Transfers Amount
Fair value, transfers between Levels 1, 2 or 3, amount
Operating Lease, Right-of-Use Asset
Operating lease right-of-use asset
Accrued Royalties
Liability related to the sale of future royalties
Liability related to the sale of future royalties - beginning balance
Liability related to the sale of future royalties - ending balance
Summary of balance sheet classification of operating lease liabilities.
Summary Of Balance Sheet Classification Of Operating Lease Liabilities [Table Text Block]
Summary of Balance Sheet Classification of Operating Lease Liabilities
Document Type
Document Type
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent, Alternative [Abstract]
Other comprehensive gain:
Entity Central Index Key
Entity Central Index Key
Line of Credit Facility [Table]
Debt Securities, Available-for-Sale [Table Text Block]
Summary of Amortized Cost and Estimated Fair Value of Available-for-sale Securities and Cash Equivalents and Gross Unrealized Gains and Losses
Payments for (Proceeds from) Tenant Allowance
Tenant improvement allowance
Investments, Debt and Equity Securities [Abstract]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation
Net decrease in cash, cash equivalents and restricted cash
Subsequent Event Type [Domain]
Fair Value Adjustment of Warrants
Change in fair value of warrant liabilities and contingent earn-out shares
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Potentially dilutive shares
Balance Sheet Related Disclosures [Abstract]
Common Stock, Par or Stated Value Per Share
Common stock, par or stated value per share
Accounting Standards Update [Domain]
Accounting Standards Update
Operating Lease, Right-of-Use Asset, Periodic Reduction
Amortization of operating lease right-of-use asset
Base Rate [Member]
Base Rate [Member]
Lessee Operating Lease Liability Lease Incentive Receivable
Lessee Operating Lease Liability Lease Incentive Receivable
Less: Lease receivable
Upfront cash payment received.
Upfront Cash Payment Received
Upfront cash payment received
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted-average remaining contractual term (in years)
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Debt Securities, Available-for-Sale
Estimated Fair Value
Debt Securities, Available-for-sale, Total
Number of Shares underlying options, Options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Issuance of common stock pursuant to stock option exercises, shares
Number of Shares underlying options, Options exercised
Debt Disclosure [Abstract]
Accrued Liabilities, Current
Accrued Liabilities, Current, Total
Accrued and other current liabilities
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Current Fiscal Year End Date
Current Fiscal Year End Date
Document Quarterly Report
Document Quarterly Report
Entity Address, State or Province
Entity Address, State or Province
The 700 Building, 300 Building and 800 Building
Seven Hundred, Three Hundred And Eight Hundred Saginaw Drive Redwood City California [Member]
Seven hundred, three hundred and eight hundred saginaw drive redwood city california member
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Number of Shares, Ending balance
Number of Shares, Beginning balance
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Gross Unrealized Gain
Common stock reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Common stock reserved for future issuance, Total
Geographical [Axis]
Geographical
Tier Five [Member]
Tier five.
Tier Five
Marketable Securities, Current
Marketable securities
Marketable Securities, Current, Total
Stock Issued During Period, Value, Stock Options Exercised
Issuance of common stock pursuant to stock option exercises
Proceeds from the sale of future royalties
Proceeds from Royalties Received
Outstanding options to purchase common stock.
Outstanding Options To Purchase Common Stock [Member]
Outstanding Options to Purchase Common Stock
Proceeds from Sale and Maturity of Marketable Securities
Sales of marketable securities
Subsequent Event [Member]
Subsequent Event
Other Assets, Noncurrent
Other noncurrent assets
Other Assets, Noncurrent, Total
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Income/(Loss)
Goodwill, Impairment Loss
Goodwill impairment
Lessee, Operating Lease, Option to Extend
Lessee, operating lease, option to extend
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
Preferred stock, $0.0001 par value; 10,000,000 shares authorized at September 30, 2025 and December 31, 2024, respectively; none issued and outstanding at September 30, 2025 and December 31, 2024, respectively
Third Party Research and Development Expenses
Third-party research and development expenses.
Third-party research and development expenses
Minimum
Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Restricted stock units granted
Financial Instrument [Axis]
Financial Instrument
Assets, Current [Abstract]
Current assets:
Amortization of intangible assets
Amortization of Intangible Assets
Amortization of Intangible Assets, Total
Level 3
Fair Value, Inputs, Level 3 [Member]
Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract]
Finite Lived Intangible Assets Future Amortization Expense [Abstract]
Segment Reporting [Abstract]
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Schedule of Financial Assets Measured at Fair Value
Liabilities, Current [Abstract]
Current liabilities:
Ending balance, shares
Shares, Outstanding
Beginning balance, shares
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Summary of Amortized Cost and Estimated Fair Value of Available-for-sale Securities by Contractual Maturity
Sublease Income
Sublease income
Less: Sublease income
Lessee, Operating Lease, Renewal Term
Lessee, operating lease option to extend lease term
Proceeds from Stock Plans
Proceeds from issuance of common stock under equity incentive plans
Commitments and Contingencies
Commitments and contingencies (Note 7)
Available for future issuance under the two zero two zero incentive award plan.
Available For Future Issuance Under The Two Zero Two Zero Incentive Award Plan [Member]
Available for Future Issuance under the 2020 Incentive Award Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Ending balance
Weighted-average grant date fair value per share, Beginning balance
General and Administrative Expense [Member]
General and Administrative
General and Administration
Operating Lease, Liability
Operating lease liability
Total operating lease liabilities
Total operating lease liabilities
Debt Instrument, Basis Spread on Variable Rate
Floating rate
Debt instrument, basis spread on variable rate
Schedule of Goodwill [Table Text Block]
Schedule of Goodwill
Depreciation, Amortization and Accretion, Net
Depreciation, Amortization and Accretion, Net, Total
Depreciation and amortization
Mature after one year through two years.
Mature After One Year Through Two Years [Member]
Mature after One Year through Two Years
Lessee, Lease, Description [Table]
Lessee Lease Description [Table]
Weighted-average remaining contractual term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Outstanding, Weighted Average Remaining Contractual Terms
Capital Expenditures Incurred but Not yet Paid
Purchases of property and equipment in accounts payable and accrued expenses and other current liabilities
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Options to purchase common stock.
Options To Purchase Common Stock [Member]
Option to Purchase Common Stock
Long-Term Debt, Type [Domain]
Weighted-average shares used to compute net loss per share attributable to common stockholders-basic
Weighted Average Number of Shares Outstanding, Basic
Weighted-average common shares used to compute net loss per share, basic
Document Information [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Aggregate intrinsic value, Options vested and exercisable
300 Saginaw Drive, Redwood City, California.
Three Hundred Saginaw Drive Redwood City California [Member]
The 300 Building
Proceeds from maturity of marketable securities.
Proceeds From Maturity Of Marketable Securities
Maturities of marketable securities
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Long-Lived Tangible Asset [Domain]
Long-Lived Tangible Asset
Debt Instrument Number of Tranche
Debt instrument number of tranche.
Debt instrument, number of tranche
Number of tranche
Area of office space leased.
Area Of Office Space Leased
Area of space leased
Subsequent Events [Text Block]
Subsequent events
Royalty Payments Termination Description
Royalty payments termination description.
Royalty payments termination description
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation expense
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Variable Rate [Domain]
Schedule of Activity of Liability Related to the Sale of Future Royalties [Table Text Block]
Tabular disclosure of activity of liability related to the sale of future royalties.
Schedule of Activity of Liability Related to the Sale of Future Royalties
Equity, Attributable to Parent
Ending balance
Beginning balance
Total stockholders' equity
Preferred Stock, Par or Stated Value Per Share
Preferred stock, par or stated value per share
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
Statement of Stockholders' Equity [Abstract]
Finite-Lived Intangible Asset, Expected Amortization, Remainder of Fiscal Year
2025 (remaining one month)
Cash Equivalents [Member]
Cash Equivalents
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Leasehold Improvements [Member]
Leasehold Improvements
Tier Four [Member]
Tier Four
Tier four.
Fair Value Disclosures [Text Block]
Fair Value Measurements
Exercise of Warrants, Shares
Exercise of warrants, shares
Exercise of warrants, Shares
Debt Instrument, Name [Domain]
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Plan Name [Domain]
Plan Name
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Tier One [Member]
Tier one.
Tier One
Schedule of Intangible Assets, Net
Business Combination, Intangible Asset, Acquired, Finite-Lived and Indefinite-Lived [Table Text Block]
Certificates of Deposit [Member]
Certificates of Deposit
Entity Address, City or Town
Entity Address, City or Town
Two thousand twenty and two thousand fourteen equity incentive plan.
Two Thousand Twenty And Two Thousand Fourteen Equity Incentive Plan [Member]
2020 Plan and 2014 Plan
Number of Reportable Segments
Number of reportable segment
Security Exchange Name
Security Exchange Name
Indefinite-Lived Intangible Assets (Excluding Goodwill)
In-process research and development - RAS Programs
Indefinite-lived Intangible Assets (Excluding Goodwill), Total
Indefinite-lived Intangible Assets (Excluding Goodwill), Beginning Balance
Indefinite-lived Intangible Assets (Excluding Goodwill), Ending Balance
Exercise of Warrants, Value
Exercise of warrants, value.
Exercise of warrants, Value
Property, Plant and Equipment, Gross
Property and equipment, gross
Property, Plant and Equipment, Gross, Total
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Ending Balance
Counterparty Name [Axis]
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Loss before income taxes
Proceeds from the Sale of Future Royalties Net of Issuance Costs
Proceeds from the sale of future royalties net of issuance costs.
Proceeds from the sale of future royalties classified as a financing activity
Proceeds from the sale of future royalties
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Number of Shares underlying options, Options vested and expected to vest
Stockholders' Equity Note [Abstract]
Cash, cash equivalents and restricted cash - end of period
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Ending Balance
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Beginning Balance
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Statistical Measurement [Domain]
Assets, Current
Total current assets
Share-Based Payment Arrangement, Expense
Stock-based compensation expense
Stock-based compensation expense
Document Period End Date
Document Period End Date
Fair Value Hierarchy and NAV [Domain]
Fair Value Hierarchy and NAV
Loss on disposal of fixed assets
Gain (Loss) on Disposition of Property Plant Equipment
Gain (Loss) on Disposition of Property Plant Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Purchased for Award
Shares purchased
Statement of Financial Position [Abstract]
Restricted Stock Units (RSUs) [Member]
Restricted Stock Units (RSUs)
Debt Securities, Available-for-Sale, Realized Loss
Realized Loss
Antidilutive Security, Excluded EPS Calculation [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation [Abstract]
Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheets
Class of Stock [Axis]
Class of Stock
700 Saginaw Drive, Redwood City, California.
Seven Hundred Saginaw Drive Redwood City California [Member]
The 700 Building
Pre-funded Warrants Issued and Outstanding [Member]
Pre-funded warrants issued and outstanding.
Pre-funded Warrants Issued and Outstanding
Commercial Paper, Not Included with Cash and Cash Equivalents [Member]
Commercial Paper
Financial Asset, Aging [Domain]
Financial Asset, Aging
Liabilities
Total liabilities
Financial Instruments [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year Two
2027
Restricted Cash
Restricted cash
Restricted Cash, Total
Deferred Revenue Arrangement, by Type [Table]
Variable Rate [Axis]
Finite-Lived Intangible Assets, Gross
Developed technology - tri-complex platform, Gross value
Finite-Lived Intangible Assets, Gross, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average shares used to compute net loss per share attributable to common stockholders-diluted
Weighted-average common shares used to compute net loss per share, diluted
Entity File Number
Entity File Number
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Net unrealized gain (loss) on marketable securities
Unrealized gain on investments, net
Cover [Abstract]
Two thousand twenty employee stock purchase plan.
Two Thousand Twenty Employee Stock Purchase Plan [Member]
2020 Employee Stock Purchase Plan
Prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Number of Shares, RSUs forfeited
Financial Asset, Aging [Axis]
Financial Asset, Aging
Supplemental Balance Sheet Disclosures [Text Block]
Balance Sheet Components
The 600 Building
Six Hundred Saginaw Drive Redwood City California [Member]
Six hundred saginaw drive redwood city california.
Tranche One [Member]
Tranche one.
Tranche One
Number of operating segment
Number of Operating Segments
Sale of Stock
Sale of Stock [Domain]
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Mature in one year or less.
Mature In One Year Or Less [Member]
Mature in One Year or Less
Net Sales
Revenue from Contract with Customer, Including Assessed Tax
Subsequent Event [Table]
Finite-Lived Intangible Assets, Net
Developed technology - tri-complex platform, Net book value
Finite-Lived Intangible Assets, Net, Beginning Balance
Finite-Lived Intangible Assets, Net, Ending Balance
Adjustments to Additional Paid in Capital, Warrant Issued
Issuance of common stock pursuant to exercise of prefunded warrants
Increase (decrease) in operating lease right-of-use asset.
Increase Decrease In Operating Lease Right Of Use Asset
Increase in operating lease right-of-use asset
Laboratory equipment.
Laboratory Equipment [Member]
Laboratory Equipment
Liability Related to the Sale of Future Royalties
Liability Related to the Sale of Future Royalties [Text Block]
The entire disclosure for information about liability related to the sale of future royalties.
Intangible Assets, Gross (Excluding Goodwill)
Intangible assets, Gross value
Intangible Assets, Gross (Excluding Goodwill), Total
New Accounting Pronouncements, Policy [Policy Text Block]
Recent Accounting Pronouncements
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Schedule of Maturities of Operating Lease Liabilities
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Award vesting period
Debt Instrument, Redemption, Description
Debt instrument redemption description
Depreciation
Depreciation, Total
Depreciation
Common Stock, Shares, Outstanding
Common stock, shares, outstanding
Common Stock, Shares, Outstanding, Beginning Balance
Common Stock, Shares, Outstanding, Ending Balance
Operating Lease, Liability, Current
Operating lease liability, current
Operating lease liability – current
Document Transition Report
Document Transition Report
Share based compensation arrangement by share based payment awards equity instruments other than options expected to vest weighted average remaining contractual term.
Share Based Compensation Arrangement By Share Based Payment Awards Equity Instruments Other Than Options Expected To Vest Weighted Average Remaining Contractual Term
Weighted-average remaining contractual term, Expected to vest
Two thousand twenty equity incentive plan.
Two Thousand Twenty Equity Incentive Plans [Member]
2020 Equity Incentive Plan
Operating Expenses
Total operating expenses
Research and Development Expense
Research and development
Total research and development expense
Asset Impairment Charges, Total
Asset Impairment Charges
Impairment of assets
Statement of Cash Flows [Abstract]
Proceeds from issuance of common stock related to employee stock purchase plan
Proceeds from issuance of common stock under employee stock purchase plan.
Proceeds From Issuance Of Common Stock Under Employee Stock Purchase Plan
Proceeds from issuance of common stock related to employee stock purchase plan
Stock Issued During Period, Value, New Issues
Issuance of common stock, net of offering costs
Redwood City, California.
Redwood City California [Member]
Redwood City Lease
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Option Activity Under the Plan
Equity [Text Block]
Common Stock
The 400 Building
Four Hundred Saginaw Drive Redwood City California [Member]
Four hundred saginaw drive redwood city california.
Earnings Per Share [Text Block]
Net Loss Per Share Attributable to Common Stockholders
Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block]
Summary of RSUs Activity Under the Plan
Net loss
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate intrinsic value
Change in Fair Value of Warrant Liability and Contingent Earn Out Shares
Change in Fair Value of Warrant Liability and Contingent Earn Out Shares
Change in fair value of warrant liabilities and contingent earn-out shares
Operating Lease, Cost
Operating lease cost
Intangible Assets, Net (Excluding Goodwill)
Intangible assets, net
Intangible assets, Net book value
Line of Credit Facility [Line Items]
Assets
Assets [Abstract]
Construction in Progress [Member]
Construction in Progress
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets, Total
Name of Property [Domain]
Name of Property
Document Fiscal Year Focus
Document Fiscal Year Focus
Expected shares to be purchased under ESPP.
Expected Shares To Be Purchased Under E S P P [Member]
Expected Shares To Be Purchased Under ESPP
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract]
Cash flows from investing activities
Commissions And Expenses
Commissions and expenses.
Commissions and expenses
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Interest Expense, Nonoperating
Interest Expense, Nonoperating, Total
Interest expense
Interest expense
Research and Development Expense [Member]
Research and Development
Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block]
Available-for-sale Securities
Accounting Standards Update 2019-12 [Member]
ASU 2019-12
Other noncurrent assets
Increase (Decrease) in Other Noncurrent Assets
Unvested restricted stock units of common stock.
Unvested Restricted Stock Units Of Common Stock [Member]
Unvested Restricted Stock Units Of Common Stock
Tier Two
Tier Two [Member]
Tier two
Fair Value Disclosures [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year One
2026
Share based compensation arrangement by share based payment award equity instruments other than options aggregate intrinsic value expected to vest.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Expected To Vest
Aggregate intrinsic value, Expected to vest
Net Income (Loss) Available to Common Stockholders, Basic, Total
Net Income (Loss) Available to Common Stockholders, Basic
Net loss attributable to common stockholders
Debt Instrument [Axis]
Share-Based Payment Arrangement [Abstract]
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized compensation cost related to ESPP
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Debt Securities, Available-for-Sale [Abstract]
Assets, Fair Value Disclosure, Total
Assets, Fair Value Disclosure
Assets fair value
Sale of Stock [Axis]
Sale of Stock
Warrant liability.
Warrant Liability
Warrant liability
Warrants outstanding [Member]
Warrants Outstanding [Member]
Warrants Outstanding
Cash Provided by (Used in) Investing Activity, Including Discontinued Operation
Net cash provided by (used in) investing activities
Schedule of accrued expenses and other current liabilities.
Schedule Of Accrued Expenses And Other Current Liabilities Table [Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Title of 12(b) Security
Title of 12(b) Security
Schedule of Segment Reporting Information, by Segment [Table]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Weighted-average exercise price, Options cancelled and forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Restricted stock units forfeited
Money Market Funds [Member]
Money Market Funds
Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year
2025 (remaining three months)
Document Information [Table]
Other Liabilities, Noncurrent
Other noncurrent liabilities
Other Liabilities, Noncurrent, Total
Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Follow-on Public Offering
Follow-on Public Offering [Member]
Follow-on Public Offering [Member]
Property, Plant and Equipment [Table Text Block]
Schedule of Property and Equipment, Net
Letters of Credit Outstanding, Amount
Letter of credit
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted-average exercise price, Ending balance
Weighted-average exercise price, Beginning balance
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Sub-tranche
Sub Tranche [Member]
Sub-tranche.
Additional Paid-in Capital [Member]
Additional Paid-In Capital
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Accrued expenses and other current liabilities
Number of voting rights per common share.
Number Of Voting Rights Per Common Share
Number of voting rights per common share
Measurement Frequency [Domain]
Measurement Frequency
Statement of Income Location, Balance [Axis]
Income Statement Location
Trading Symbol
Trading Symbol
Loan Amount Drawn
Loan amount drawn.
Loan amount drawn
Subsequent Event Type [Axis]
Share based compensation arrangement by share based payment award equity instruments other than options expected to vest weighted average grant date fair value.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Expected To Vest Weighted Average Grant Date Fair Value
Weighted-average grant date fair value per share, Expected to vest
Warrants.
Warrants [Policy Text Block]
Warrants
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract]
Cash flows from financing activities
Fair Value, Recurring [Member]
Fair Value, Recurring
Entity Ex Transition Period
Entity Ex Transition Period
Lessee, Operating Lease, Liability, to be Paid
Total undiscounted lease payments
Undiscounted lease payments
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: Imputed interest
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Purchase price rate
Equity Components [Axis]
Equity Components
Sublease Agreement
Sublease Agreement [Member]
Sublease agreement.
Nonoperating Income (Expense)
Total non-operating income, net
Equity Component [Domain]
Equity Component
Asset Class [Axis]
Asset Class
Goodwill and Intangible Assets Disclosure [Abstract]
Upfront fee percentage
Debt Instrument UpFront Fee Percentage
Debt instrument upfront fee percentage.
Royalty rate projections description
Royalty Rate Projections Description
Royalty rate projections description.
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock related to employee stock purchase plan, shares
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Two thousand twenty equity incentive plan.
Two Thousand Twenty Equity Incentive Plan [Member]
2020 Equity Incentive Plan
Tranche Two [Member]
Tranche two.
Tranche Two
Depreciation, Depletion and Amortization, Nonproduction, Total
Depreciation, Depletion and Amortization, Nonproduction
Share based compensation arrangement by share based payment award equity instruments other than options expected to vest outstanding number.
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Expected To Vest Outstanding Number
Number of Shares, Expected to vest
Common Stock, Voting Rights
Common stock, voting rights
Maximum [Member]
Maximum
Liabilities, Fair Value Disclosure
Liabilities fair value
Liabilities fair value
Statistical Measurement [Axis]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Weighted-average exercise price, Options exercised
Finite-Lived Intangible Assets, Accumulated Amortization
Developed technology - tri-complex platform, Accumulated amortization
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Common stock, $0.0001 par value; 300,000,000 shares authorized as of September 30, 2025 and December 31, 2024, respectively; 189,710,951 and 185,896,625 shares issued and outstanding as of September 30, 2025 and December 31, 2024, respectively
The 900 Building
Nine Hundred Saginaw Drive Redwood City California [Member]
Nine Hundred Saginaw Drive Redwood City California [Member]
Comprehensive Income (Loss), Net of Tax, Attributable to Parent [Abstract]
Comprehensive loss:
Amortization of issuance costs
Amortization of Debt Issuance Costs
Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block]
Schedule of Future Amortization Expense
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Available for future issuance under the two zero two zero employee stock purchase plan.
Available For Future Issuance Under The Two Zero Two Zero Employee Stock Purchase Plan [Member]
Available for Issuance under the 2020 Employee Stock Purchase Plan
Royalties Earned Percentage of Revenue
Royalties earned percentage of revenue.
Percentage of royalty payments received
Entity Registrant Name
Entity Registrant Name
Debt Disclosure [Text Block]
Term Loan Facility
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Loss
Deferred Revenue Arrangement [Line Items]
Other income (expense), net
Other Nonoperating Income (Expense)
Other Nonoperating Income (Expense), Total
Subsequent Events [Abstract]
Debt Securities, Available-for-Sale, Gain (Loss)
Debt Securities, Available-for-Sale, Gain (Loss), Total
Available-for-sale Securities
Measurement Frequency [Axis]
Measurement Frequency
Proceeds from Issuance of Common Stock
Net proceeds from issuance
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Liability Class [Axis]
Liability Class
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive income
Consolidation Items [Axis]
Marketable Securities
Marketable Securities [Member]
Marketable securities.
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Number of Shares, RSUs granted
Assets
Total assets
Property, Plant and Equipment [Table]
Schedule Of Property Plant And Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Weighted-average remaining contractual term, Options vested and exercisable
Class of Financing Receivable [Domain]
Income Statement [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
Aggregate intrinsic value
Stock Issued During Period, Shares, New Issues
Issuance of common stock upon offering, net of offering costs, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Number of Shares, RSUs vested
Net loss per share attributable to common stockholders, diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Schedule of Segment Reporting Information, by Segment [Table Text Block]
Schedule of Significant Segment Expenses
Operating Segments [Member]
Operating Segments
Dividends, Common Stock
Common stock, dividends declared
Dividends, Common Stock, Total
City Area Code
City Area Code
Accrued expenses and other current liabilities.
Accrued Expenses And Other Current Liabilities
Accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Lease incentive receivables
Lease Incentive Receivables
This item represents a receivable for an incentive or inducement contractually stipulated between parties to a lease whereby the lessor has committed to provide the entity (lessee) with a cash payment as inducement to enter the lease.
Line of Credit Facility, Maximum Borrowing Capacity
Credit facility, maximum borrowing capacity
Aggregate tranches totaling amount
Counterparty Name [Domain]
Computer equipment and software.
Computer Equipment And Software [Member]
Computer Equipment and Software
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock related to employee stock purchase plan
Operating Lease, Weighted Average Remaining Lease Term
Operating lease, weighted average remaining lease term
Segment Reporting Information [Line Items]
Lease, Cost
Total operating lease cost, net
Liability Related to the Sale of Future Royalties [Member]
Liability related to the sale of future royalties.
Liability Related to the Sale of Future Royalties
Deferred Revenue Disclosure [Abstract]
Royalty Pharma [Member]
Royalty pharma.
Royalty Pharma
Property, Plant and Equipment, Net
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net, Beginning Balance
Property, Plant and Equipment, Net, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Number of Shares underlying options, Options vested and exercisable
Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation
Cash, cash equivalents and restricted cash - end of period
Cash, cash equivalents and restricted cash - beginning of period
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Operating Income (Loss)
Loss from operations
Retained Earnings [Member]
Accumulated Deficit
Increase (Decrease) in Deposit Assets
Increase (Decrease) in Deposit Assets, Total
Long-term deposits
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Operating Lease, Weighted Average Discount Rate, Percent
Operating lease, weighted average discount rate
Operating Lease, Liability, Noncurrent
Operating lease liability, noncurrent
Operating lease liability – noncurrent
Liability Related to the Sale of Future Royalties, Policy [Policy Text Block]
Disclosure of accounting policy for liability related to the sale of future royalties.
Liability Related to the Sale of Future Royalties
Fair Value, Inputs, Level 1 [Member]
Level 1
Class of Stock [Line Items]
Class Of Stock [Line Items]
Cash Provided by (Used in) Financing Activity, Including Discontinued Operation
Net cash provided by financing activities
Lease, Cost [Table Text Block]
Summary of Components of Lease Costs
Proceeds From Issuance Of Common Stock From At The Market Offering
Proceeds from issuance of common stock from at the market offering.
Proceeds from issuance of common stock upon at-the-market offering, net of issuance costs
Deferred Income Tax Liabilities, Net
Deferred tax liability
Deferred Income Tax Liabilities, Net, Total
Deposits Assets, Noncurrent
Long-term deposits
Nonoperating Income (Expense) [Abstract]
Non-operating income (expense):
US Government Corporations and Agencies Securities [Member]
U.S. Government and Agency Securities
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Outstanding Potentially Dilutive Shares Excluded from Calculation of Diluted Net Loss Per Share
Corporate Debt Securities [Member]
Corporate Bonds
Debt Securities, Available-for-Sale [Table]
Debt Securities Available For Sale [Table]
Entity Interactive Data Current
Entity Interactive Data Current
Income Statement Location
Statement of Income Location, Balance [Domain]
Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract]
Cash flows from operating activities
Furniture and Fixtures [Member]
Furniture and Fixtures
Non-cash interest expense on liability related to sale of future royalties
Paid-in-Kind Interest
Accretion (Amortization) of Discounts and Premiums, Investments
Net amortization of premium or discount on marketable securities
Other noncurrent liabilities
Increase (Decrease) in Other Noncurrent Liabilities
Entity Tax Identification Number
Entity Tax Identification Number
Lessee operating lease liability payments due after year four.
Lessee Operating Lease Liability Payments Due After Year Four
Thereafter
Long-Term Debt, Type [Axis]
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Organization
Local Phone Number
Local Phone Number
Debt Securities, Available-for-Sale, Unrealized Gain
Gross Unrealized Gain
Other Liabilities, Current
Other
Other Liabilities, Current, Total
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation expense related to unvested stock options
Weighted Average Number of Shares Outstanding, Diluted [Abstract]
Denominator:
Accounting Policies [Abstract]
Numerator:
Net Income (Loss) Attributable to Parent [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Year Four
2029
Class of Stock [Domain]
Class of Stock
Commercial Paper [Member]
Commercial Paper
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation expense, weighted-average period of recognition
Accrued Professional Fees, Current
Accrued professional services
Stock, Class of Stock [Table]
Schedule Of Stock By Class [Table]
Entity Emerging Growth Company
Entity Emerging Growth Company